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Bridging research and practice: Models for dissemination and implementation research antibiotics for face infection panmycin 250 mg with mastercard. Planning for the sustainability of communitybased health programs: Conceptual frameworks and future directions for research infection 2 hacked panmycin 500 mg generic, practice and policy virus 36 discount panmycin 500 mg online. Sustaining interventions in community systems: On the relationship between researchers and communities can you take antibiotics for sinus infection while pregnant discount panmycin 500mg otc. Mobilizing communities to implement evidence-based practices in youth violence prevention: the state of the art. Diffusion of innovations in service organizations: Systematic review and recommendations. Fostering implementation of health services research fndings into practice: A consolidated framework for advancing implementation science. The quality implementation framework: A synthesis of critical steps in the implementation process. Unpacking prevention capacity: An intersection of research-to-practice models and community-centered models. Assessing and enhancing readiness for change: Implications for technology transfer. Rating the states: An assessment of the nation’s attention to the problem of drunk driving & underage drinking. Association between state level drinking and driving countermeasures and self reported alcohol impaired driving. The legislative impact of social movement organizations: the anti-drunken driving movement and the 21-year-old drinking age. Strategizer 54 A community’s call to action: Underage drinking and impaired driving. Developing a community science research agenda for building community capacity for effective preventive interventions. The longitudinal effect of technical assistance dosage on the functioning of Communities That Care prevention boards in Pennsylvania. The role of a state-level prevention support system in promoting high-quality implementation and sustainability of evidence-based programs. What strategies are used to build practitioners’ capacity to implement communitybased interventions and are they effectivefi Building collaborative capacity in community coalitions: A review and integrative framework. Toward a comprehensive strategy for effective practitioner–scientist partnerships and larger-scale community health and well-being. Evaluating community-based collaborative mechanisms: Implications for practitioners. Identifying training and technical assistance needs in community coalitions: A developmental approach. Bridge-It: A system for predicting implementation fdelity for school-based tobacco prevention programs. Bridging the gap between prevention research and practice: the interactive systems framework for dissemination and implementation. Strategies for enhancing the adoption of schoolfibased prevention programs: Lessons learned from the Blueprints for Violence Prevention replications of the Life Skills Training program. Finding the balance: Program fidelity and adaptation in substance abuse prevention: A state-of-the-art review. A review of research on fdelity of implementation: Implications for drug abuse prevention in school settings. Disseminating effective community prevention practices: Opportunities for social work education. Administration and Policy in Mental Health and Mental Health Services Research, 40(6), 482-493. Implementation, sustainability, and scaling up of social-emotional and academic innovations in public schools. Building capacity and sustainable prevention innovations: A sustainability planning model. Sustainability of evidence-based healthcare: Research agenda, methodological advances, and infrastructure support. The sustainability of new programs and innovations: A review of the empirical literature and recommendations for future research. Sustaining evidencebased interventions under real-world conditions: Results from a large-scale diffusion project. Preventing college women’s sexual victimization through parent based intervention: A randomized controlled trial. Standards of evidence for efcacy, effectiveness, and scale-up research in prevention science: Next generation. Substance use disorders range in2 severity, duration, and complexity from mild to severe. While historically the great majority of treatment has occurred in specialty substance use disorder treatment programs with little involvement by primary or general health care, a shift is occurring toward the delivery of treatment services in general health care practice. For those with mild to moderate substance use disorders, treatment through the general health care system may be sufcient, while those with severe substance use disorders (addiction) may require specialty treatment. Research shows See Chapter 6 Health Care Systems that the most effective way to help someone with a substance and Substance Use Disorders. With this recognition, screening for substance misuse is increasingly being provided in general health care settings, so that emerging problems can be detected and early intervention provided if necessary. The addition of services to address substance use problems and disorders in mainstream health care has extended the continuum of care, and includes a range of effective, evidence-based medications, behavioral therapies, and supportive services. However, a number of barriers have limited the widespread adoption of these services, including lack of resources, insufcient training, and workforce shortages. This is particularly true for5 the treatment of those with co-occurring substance use and physical or mental disorders. The great majority of treatment has occurred in specialty substance use disorder treatment programs with little involvement by primary or general health care. However, a shift is occurring to mainstream the delivery of early intervention and treatment services into general health care practice. However, an insuffcient number of existing treatment programs or practicing physicians offer these medications. Well-supported scientifc evidence shows that these brief interventions work with mild severity alcohol use disorders, but only promising evidence suggests that they are effective with drug use disorders. The goals of treatment are to reduce key symptoms to non-problematic levels and improve health and functional status; this is equally true for those with co-occurring substance use disorders and other psychiatric disorders. Treatments using these evidence-based practices have shown better results than non-evidence-based treatments and services. In this regard, substance use disorder treatment is effective and has a positive economic impact. An integrated that treatment also improves individuals’ productivity,11 system of care that guides and 11,12 13-15 tracks a person over time through health, and overall quality of life. In addition, studies a comprehensive array of health show that every dollar spent on substance use disorder services appropriate to the individual’s treatment saves $4 in health care costs and $7 in criminal need. These common but less severe disorders often respond to brief motivational interventions and/or supportive monitoring, referred to as guided self-change. To address the spectrum of substance use problems and disorders, a continuum of care provides individuals an array of service options based on need, including prevention, early intervention, treatment, and recovery support (Figure 4. Traditionally, the vast majority of treatment for substance use disorders has been provided in specialty substance use disorder treatment programs, and these programs vary substantially in their clinical objectives and in the frequency, intensity, and setting of care delivery. Substance Use Status Continuum Substance Use Care Continuum Enhancing Health Primary Early Treatment Recovery Prevention Intervention Support Promoting Addressing Screening Intervening through medication, Removing barriers optimum physical individual and and detecting counseling, and other supportive and providing and mental environmental substance use services to eliminate symptoms supports to health and wellrisk factors problems at and achieve and maintain sobriety, aid the longbeing, free from for substance an early stage physical, spiritual, and mental health term recovery substance misuse, use through and providing and maximum functional ability. Includes through health evidencebrief Levels of care include: a range of social, mmunications and based intervention, educational, • Outpatient services; access to health programs, as needed. This chapter describes the early intervention and treatment components of the continuum of care, the major behavioral, pharmacological, and service components of care, services available, and emerging treatment technologies: $ Early Intervention, for addressing substance misuse problems or mild disorders and helping to prevent more severe substance use disorders. The goals of early intervention are to reduce the harms associated with substance misuse, to reduce risk behaviors before they lead to injury,18 to improve health and social function, and to prevent progression to a disorder and subsequent need for specialty substances use disorder services. Early intervention services may be considered the bridge between prevention and treatment services. For individuals with more serious substance misuse, intervention in these settings can serve as a mechanism to engage them into treatment. In 2015, an estimated 214,000 women consumed alcohol while pregnant, and an estimated 109,000 pregnant women used illicit drugs.

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The content of records antibiotics for acne and rosacea panmycin 250 mg free shipping, described in the next section of • Facts should be recorded using behavioral this chapter fish antibiotics for human uti cheap panmycin 500mg, provide accountability and may descriptors (see next section) antibiotics origin cheap 500mg panmycin. Serve as a therapeutic tool for the • Once recorded virus 868 generic panmycin 250mg amex, information should not be caseworker and the family. Errors can be noted as demonstrate the way in which the caseworker an addendum to a specific note. Structured and timely presentation or in other open spaces where others might of factual information leads to more indepth have access to them. Child Protective Services: A Guide for Caseworkers 141 • Families have a right to anything are based on facts, not baseless judgments. Smith before documenting any parts of the case appeared to be intoxicated, his eyes were red, record. Caseworkers should only record he had difficulty standing without losing his what they are willing to share directly with balance, and his breath smelled of alcohol at 10 family members. The language chosen should be based on observations of specific behaviors and conditions or obtained by asking open ended questions to clarify opinions offered by others. This approach increases the likelihood that conclusions and decisions 142 Child Protective Services: A Guide for Caseworkers 12. The worker should also well as the location and purpose of these document if and why a safety plan was not contacts. Child Protective Services: A Guide for Caseworkers 145 A form of consultative supervision is reflective the following sections discuss both supervision that creates an opportunity for practices indepth. However, brief caseworkers to consider, debate, and analyze definitions are listed here: confusing and even conflicting data regarding family situations (Lietz, 2009). Using a reflective supervision approach, workers to fulfill their responsibilities to particularly during group supervision, offers interview, conduct assessments, develop plans, the opportunity for peer support and multiple implement change strategies and interventions, perspectives about challenging situations and and evaluate changes in the risk and protective enhance critical thinking about key decisions factors that brought families to the attention (Lietz, 2008). Implementing consultative supervision occurs through discussion about specific 13. A supervisor might stop by to dynamics and functioning, and identifies ask about a recent field visit or a worker and examples of implicit bias that may pose the supervisor might have conversations as they need for alternate perspectives (Ferguson, travel together on their way to court. Supervisory meetings should be to develop a team identity, which promotes private to permit indepth discussions without peer support, the ability to communicate and interruption. Ideally, the caseworker and work together, develop a common work ethic, supervisor will contract with each other to and establish a commitment to best practice develop a mutual understanding about (Hanna & Potter, 2012). Examples of different perspectives in context of discussions topics of discussions about families include: about families and their children. While this seems very Coaching is a process for supporting basic, it often is hard to do. The coaching process and does not have a private office, this may mean skills may be used in individual and group finding other ways to hold supervision, such as supervision. An advantage of integrating reserving the use of a conference or interview coaching within the supervisory process is that room, or if necessary, by hanging a sign in front supervisors often already have these skills, and of the cubicle to try to prevent interruptions. Each of these skills may active listening skills are essential in a coaching be used in both formal and informal coaching model of supervision. The “art” of listening can’t be accomplished if presence has not first been established. Making eye contact, facing each other, and being attentive to both verbal and nonverbal cues are essential parts of listening Example: Verbal encouragers, like “hmm,” “go on,” and nodding your head to acknowledge you heard what is being said 2 Information in this section based on the Atlantic are examples of demonstrating listening. Coast Child Welfare Implementation Center (2012), Coaching in child welfare curriculum. Giving strengths-based feedback is workers use these skills in sessions with families, essential to the coaching process. This means supervisors use reflection and ask open-ended that even if the supervisor is in a position clarifying questions to explore the issue(s) to offer constructive feedback, it should be the caseworker has brought to supervision. This means reflecting back the content of the the supervisor should also use this skill by caseworker’s words to affirm that the supervisor asking the caseworker for feedback on the understands. Feedback should be: with the emotion the caseworker may be • Frequent enough to sustain expected evoking when presenting a particularly troubling practice situation. It also involves using summarization to check in that the supervisor and caseworker are • Direct and related to a performance issue on the same page with respect to the focus of • Behavioral in that it is focused on changes the supervisory session that day. They • Helpful in that the receiver perceives the received their eviction notice on Friday motives of the giver as constructive and only have two weeks to find another apartment, and the mother seems unable • Clear so that the feedback and intention is to cope, as this is one more thing on understood top of a series of crises this family has experienced. This involves the supervisor overwhelmed because you can’t imagine and caseworker setting clear action items finding a livable apartment for a mother and together and implementing plans for following three children in only two weeks within the up. You really want to help this constructing strategies to address breakdowns family avoid having to move into a shelter. What have I missed with how you see the Example: Now that you have set a goal to problemfi Last week we talked about intended to move the caseworker into reflection how you were going to have a courageous and discovery. Brown by exploring that begin with “what” or “how” keep the whether she has initiated contact with conversation focused and empower the her boyfriend again even though she has caseworker to consider options for problem said there was no way she was going back solving. To coach the caseworker, the supervisor to him after what he did to her and her must focus on supporting the caseworker to 9-year-old son. What are your thoughts might you try differently next time you about the way to handle this situationfi From my review of your progress notes, it seemed like you were using your new motivational interviewing skills. I also noticed that your use of summarization is helping the family to remain focused during your visits. Caseworker: It feels a little awkward to me since it is still new, but I am determined to continue to try it out. Supervisor: So even though it can be challenging, it sounds like you are taking advantage of this learning opportunity and also recognizing how these skills can beneft your work. I am going to keep practicing with the Gordon family and emphasize ways to recognize their change talk. Supervisor: You should be proud of your willingness to practice motivational interviewing skills while they are still fresh in your mind. It shows that you are serious about your skills development and helping your families. I am trying very hard to emphasize partnership, respect, and compassion in my work with families. Supervisor: I know from past conversations that you were experiencing a breakdown with the Andrews family. How could you use what you learned from the motivational interviewing training and your experience with the Gordon family to increase their readiness to changefi Caseworker: I am so frustrated with the Andrews family and my frustration is growing by the minute. And as far as I can tell, they haven’t made any progress to implement their family plan. You are a dedicated caseworker who always keeps appointments with your families, you have conversations with each of the family members at your visits, and your families report that you are a great support. And, I noticed that you recently used motivational interviewing and strengths-based engagement skills to include all members of the Gordon family in developing their family plan. I also noticed that the Andrews family didn’t have much input into the creation of their plan. Caseworker: Yes, due to time constraints, I was unable to get them involved in the development of their plan. Supervisor: How does the approach you used with the Andrews family demonstrate partnership, respect, and compassionfi Thank you for pointing that out, I have been so frustrated with this family that I failed to realize that I didn’t even try to include them in the planning. Maybe I need to be more empathic by tuning into the family’s needs and reengage the family by asking them what their priorities are. During weekly supervisory sessions, the full coaching process may be used as reflected in exhibit 13. This involves: • Beginning the session to center together, making sure both are 100% present • Clarifying the focus for the supervisory coaching session; if the caseworker had developed goals and an action plan during the previous session, this session might begin by understanding what did and did Exhibit 13. The two are meeting in Carolyn’s office after Mattie requested via email for Carolyn to meet with her. Carolyn: I got your email and I know there is a lot that you wanted to talk about today.

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Clinical utility of of acute and subacute hearing loss: a review of pharmacotherapy antibiotics immune system panmycin 500 mg amex. Clinical symptoms are non-specific (fatigue bacteria quorum sensing cheap panmycin 250 mg on-line, malaise bacteria bugs panmycin 250mg otc, fever antimicrobial phone case order 500mg panmycin otc, anorexia, nausea, weight loss) and/or attributable to the involvement of one or more organ systems. Pathogenesis involves circulating autoantibodies, immune complexes, and complement deposition leading to cell and tissue injury. Nucleosomes are presented as autoantigens to pathogenic T helper and B cells and T regulatory cells are significantly decreased. Current management/treatment Therapy entails conventional immunosuppressive agents (cyclophosphamide, azathioprine, prednisone, methotrexate, cyclosporine and mycophenolate mofetil) and newer biologic therapies (rituximab, belimumab). Autologous hematopoietic stem cell transplantation has been used as a salvage therapy in select patients. In general, intensity of treatment is guided by the most severe organ involvement. Scores are converted to an A-E alphabetical assessment that provides treatment recommendations (Symmons, 1988). Prolonged treatments have been reported but efficacy and rationale behind this approach is questionable. Rapid reduction of antibodies and improvement of disease activity by immunoadsorption in Chinese patients with severe systemic lupus erythematosus. References of the identified articles were exchange and immunoadsorption in systemic lupus erythematosus and searched for additional cases and trials. In these clinical scenarios, the patient is not at increased risk of thrombosis or bleeding because, while elevated, the platelets are functionally normal. Arterial or venous thromboembolic events include microvascular thrombosis, stroke and transient ischemic attacks, myocardial infarction, venous thromboembolism, and first-trimester pregnancy loss (either spontaneously or during an otherwise hypercoagulable state). Therisk of bleeding increases significantly when the platelet count is >1,000-1,500 fi 109/L. Risk of hemorrhage and thrombosis also appears to be increased when the white blood cell count is also elevated. Ifperformed,splenectomycanbeassociatedwithextreme“rebound” thrombocytosis (>1,000 fi 109/L) in 5% of cases with postoperative thrombosis (10%) and bleeding (14%); however, platelet count does not predict thrombohemorrhagic complications. Current management/treatment Low-dose aspirin is indicated for thromboprophylaxis in low risk patients and is also useful in reducing vasomotor symptoms, such as headache, tinnitus, ocular disturbances and erythromelalgia. There is no difference in the 1-year complete response rate, or rate of thrombosis/hemorrhage or transformation rate at 2 years between ruxolitinib and standard of care. Platelet count should be normalized before surgery, particularly splenectomy, to minimize complications and avoid rebound thrombocytosis. Venous and arterial thromboembolic events aretreatedinaccordancewithnationalguidelinesand institutional policy. Patients with extreme thrombocytosis and hemorrhage should be treated to lower the platelet count with medical therapy and/or thrombocytapheresis. Although the therapeutic mechanisms are not well defined, rapid cytoreduction is believed to ameliorate prothrombotic factors associated with the dysfunctional platelets. Thrombocytapheresis is only a bridging therapy and thus, maintaining the patient on cytoreduction therapy is essential to prevent platelet rebound after the procedure. Elective thrombocytapheresis should also be considered for cytoreduction of patients at increased risk of major hemorrhage when hydroxyurea is contraindicated (such as in pregnancy) or in situations rapid reduction is necessary (such as the requirement for emergent surgery). Platelet-lowering agents must be given to prevent rapid re-accumulation of circulating platelets whenever possible. Anticoagulant ratio of whole blood: anticoagulant should be 1:6-12; heparin should be avoided to prevent ex-vivo platelet clumping. It is important to maintain normal count until cytoreductive therapy takes effect. Without an informative clinical history, platelet count of fi450-600 fi 109/L may be enough. Hematology thrombocytosis, essential thrombocythemia, polycythemia vera, myeloproAm Soc Hematol Educ Program. References of the identified articoncentration monitor alarm in therapeutic thrombocytapheresis. The role patient selection, and perioperative platelet management: outcomes and lesof thrombocytapheresis in the contemporary management of hypersons from 3 decades of splenectomy for myelofibrosis with myeloid metathrombocytosis in myeloproliferative neoplasms: a case-based review. Polycythemia vera and essential essential thrombocythaemia and very high platelets count: what is the thrombocythemia: algorithmic approach. However, mutations in complement genes are not always present in those with disease and some with mutations do not appear to have disease, suggesting incomplete penetrance and/or other genetic modifiers of function. Because these genetic mutations are not all directly impactful on the complement cascade, therapy with eculizumab may not be beneficial. Further experience is needed to determine if plasma can be a source for therapeutic intervention, although intuitively, plasma should contain the deficient coagulation factors absent or decreased in affected patients. References of the identified articles were Lemaire M, Fremeaux-Bacchi V, Schaefer F, et al. Successful treatment of atypical Miyata T, Uchida Y, Ohta T, Urayama K, Yoshida Y, Fujimura Y. Relative role of genetic complement hemolytic uremic syndrome registry: initial analysis of 146 patients. Incomplete forms with mild or no typical hematologic features, account for ~20% of cases. Disease may present with an insidious onset at any age, but many cases present in the first few months of life and 40% occur in young adults. The primary pathogenic event appears to be endothelial injury leading to formation of platelet-fibrin hyaline microthrombi, which occlude arterioles and capillaries. Complement activating conditions, such as infection, pregnancy, autoimmune disease, transplantation, or drugs, may trigger clinical disease in presence of these mutations. A history of recurrent infections from Streptococcus or other encapsulated microorganisms such as Neisseria meningitidis or Haemophilus influenza should suggest a familial etiology. Technical notes As many affected patients are children, establishment of vascular access, circuit priming, and calcium supplementation are of special concern. An audit analysis of guideline for the investigation and initial therapy of diarrhea negative (atypical) hemolytic uremic syndrome. Atypical hemolytic uremic synFactor B, Factor H, Factor I, membrane cofactor protein, plasmapheresis, drome: a meta-analysis of case reports confirms the prevalence of plasma exchange for articles published in the English language. Factor H autoantibody is dict recurrence and graft outcomes in adult renal transplant recipients associated with atypical hemolytic uremic syndrome in children in the with atypical hemolytic uremic syndrome. Efficacy ment mutations on clinical characteristics in atypical hemolytic uremic and safety of eculizumab in adult patients with atypical hemolytic uresyndrome. Efficacy and safety of therapeutic autoantibody-associated hemolytic uremic syndrome in children. Use of Johnson S, Stojanovic J, Ariceta G, Bitzan M, Besbas N, Karpman D, eculizumab for atypical hemolytic uraemic syndrome and C3 Frieling M, Landau D, Langman C, Licht C, Pecoraro C, Riedll M, glomerulopathies. Current management/treatment Initial management involves immediate discontinuation of suspected drug, or reduction of dose when discontinuation is not a therapeutic option. Supportive care and other interventions reported for specific drugs include gemcitabine: dialysis, antihypertensives, corticosteroids, rituximab; quinine: corticosteroids, antiplatelet agents; bevacizumab: steroids, cyclophosphamide; cyclosporine/tacrolimus/sirolimus: use of alternate immunosuppression (see separate fact sheet). Pathogenesis is multifactorial including autoimmunity, drug-dependent antibodies and endothelial toxicity. Seventeen required dialysis and 14 went on to develop chronic kidney disease; 9 patients died (Page, 2017). Rapid and complete resolution of quinine, ticlopidine, clopidogrel, thienopyridine, sirolimus, bevacizumab for chemotherapy-induced thrombotic thrombocytopenic purpura/hemolytic reports published in the English language. Gemcitabine-induced thrombotic microsirolimus and cyclosporine as salvage therapy for graft-versus-host disangiopathy. A total of 3,842 people were affected by a virulent and uncommon strain of enteroaggregative hemorrhagic E. Stx binds to multiple cells in the kidney and causes a spectrum of renal injury, including vascular endothelial cell damage, thrombotic occlusion of the capillary lumen, glomerular endothelial cell swelling, apoptosis of glomerular and tubular cell, and extensive cortical necrosis in the kidneys. The severity of acute illness, particularly central nervous system impairment and the need for dialysis is strongly associated with a worse long-term prognosis. Mortality is between 1-5% but up to 30% of patients may have long term complications including; hypertension, end stage renal disease requiring renal transplantation, diabetes and neurological symptoms. Current management/treatment Supportive care is the mainstay of therapy including fluid management, treatment of hypertension and renal replacement therapy. Stx has been shown in vitro and in vivo to activate the alternative complement pathway.

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The minimal difference may be due to antibiotic quiz pharmacology cheap panmycin 500 mg with visa the possibility that the question on the history of sexually transmitted disease was not totally understood by the subjects and hence they may not have provided the required information antibiotic cream discount panmycin 250mg line. Lack of use of sanitary pads was found to antibiotic resistance target protein purchase panmycin 500mg on-line be a risk factor for cervical dysplasia in Trivandrum (Varghese et al virus vs disease buy panmycin 250 mg on-line. Genital hygiene is likely to be a reflection of the living conditions, amenities etc. Infections of the lower genital tract are very common in this population and 60–70% of women in all the age groups had ‘inflammation’ on their cervical smears. It is possible that these women harbour many bacterial and viral infections and chronic cervicitis and progression to various grades of dysplasias are likely in them. This is an indication that the responses were true and that those who had premarital partners were likely to have extramarital partners also. Eighty three percent of men who had extramarital partners visited commercial sex workers. Regarding their own sexual behaviour, the answers to premarital and extramarital partners were less strongly agreed upon by women. This is likely to be true, as the majority of men who had extramarital partners had been visiting commercial sex workers. In the case of women, those with extramarital partners had a prevalence of 24% compared to 8% in those who did not have partners. Fifteen percent of husbands were reported to have contact with commercial sex workers in the Trivandrum study. Of those who reported having extramarital partners 91% were in the lowest income group and 38% were in the group with the lowest level of education. Hospital attendees in India may be very different from the general population and regions within India are not strictly comparable in many aspects. Collinearity was controlled to a certain extent by forming factors which are representative by combining correlated variables. Socio-economic status exerted its effect independent of the variables, genital hygiene and sexual behaviour in this study. Low socio-economic status could be a reflection of many of the living conditions and behavioural patterns. The hygienic practices of both the husband and the wife were important and emerged as significant. The behavioural pattern of asymptomatic Greek women and that of women in South India are obviously not comparable. Moreover, frequent washing of genitalia during menstruation may not be a hygienic practise and might lead to infections. This study was among adolescent girls in Sweden who are not comparable to the housewives of Kerala, but the common factor of multiple partners suggest that there is a biological basis for this association. There were only very few studies on sexual behaviour and cervical neoplasia from India and one such study in rural India reported extramarital partners for women as an independent risk factor for cervical cancer (Biswas et al. It is conceivable that transmission occurred through contact as infections in infants have been in the oral cavity and nasopharynx. External genitalia also have been identified as the site of infection in infants and virgins. However, for the infection to reach the uterine cervix epithelium there may have to be co-factors. The area was not randomly selected and thus the results have a limitation in generalising to other areas. The sexual promiscuity reported in this study is likely to be an underestimate of the true behaviour. Type specific comparisons were not made as the subtypes were made available later only. Prevention strategies are based on the control of sexual transmission and the possibility of vaccination. If an efficient and cheap vaccine is made available it can be considered for mass vaccination, but no such options are available at present. Poor socio-economic status is a much more prevalent factor and it seems to exert its effect independent of poor genital hygiene and sexual promiscuity. The population attributable risk percentage was 40% for low socio-economic status making it the most feasible intervention. Genital hygiene is an important aspect of the reproductive health of the women and special emphasis has to be placed on this aspect. Improvement in 67 living standards and health education can improve the genital hygiene. The reported promiscuity is an underestimate of the true figure and hence the low population attributable risk percentage for this factor. It may be difficult in the older generations but certainly has to be considered for the younger generations who are exposed to the emerging social and cultural changes. More than screening the facilities for optimal treatment of screen detected lesions is essential for the screening programme to be successful and this is a major limitation in many low resource countries with a high incidence of cervical cancer. An alternative strategy like ‘visual inspection’ was tested and was not found to be a good option in our settings (Varghese et al. Health care workers in the community, whose mandate is to provide health education, need to be made aware of the changing disease patterns and the importance of primary prevention strategies for chronic diseases. The services of the print and electronic media should also be utilised for providing health education messages to the community. Two thousand five hundred and thirty five women were interviewed for details on sexual behaviour and genital hygiene. Premarital sex is considered forbidden and multiple partnerships for women are negligible. Extramarital sexual relations of men seem to be in frequenting commercial sex workers. Their valuable advice and comments helped me substantially to improve the quality of this work. Thanks are also due to the Government of Finland and the Cancer Society of Finland for providing the financial support for my studies in the University of Tampere through the agreement between the Ministry of Education in India and Finland. I wish to express my warmest gratitude to my wife, daughter, mother and brothers for their patience and loving support during my time away from the family and for all their care and concern. Canadian Task Force (1976): Cervical cancer Screening Programme: Epidemiology and natural history of carcinoma of the cervix. Home dampness and molds as determinants of respiratory symptoms and asthma in pre-school children. Reduction in the cumulative incidence rate of cervical cancer by one life time selective screening. Karlsson R, Jonsson M, Edlunk K, Evander M, Gustavson A, Boden E, Rylander E and Wadell G (1995): Lifetime number of partners as the only independent risk factor for human papillomavirus infection: a population-based study. Munoz N, Herrero R, Lazcano E, Posso H, Matos E, Sukvirach S, Meijer C, and Walboomers J (2000). Parazzini F, La Vecchia C, Negri E, Fedele L, Franceschi S and Gallotta L (1992): Risk factors for cervical intra epithelial neoplasia. Sankaranarayanan R, Varghese C, Duffy S W, Padmakumary G, Day N E and Nair M K (1994): Diet and lung cancer: A case-control study in Kerala, India. Br J Cancer 75: 436-440 Winkelstein W Jr (1977): Smoking and cancer of the uterine cervix: Hypothesis. E Department of Microbiology and Infectious Diseases, the Royal Women’s Hospital, Parkville, Vic. Background: Cervical cancer is the second commonest cancer amongst Sri Lankan women. Methods: Primigravids attending Colombo North Teaching Hospital antenatal clinics were recruited over 8 months as surrogates for women who have recently become sexually active. The total knowledge score ranged from zero (379/665) to nine (2/665), with a mean of 0. Among those aware of Pap screening, generally there were favourable attitudes to having a test. These data have implications for acceptance of the vaccine and any future expansion of cervical screening with newer, more cost-effective technologies. Items were modified to ensure 2009, but have been available in the private sector only since cultural appropriateness. Lack pilot tested for readability and ease of understanding on 10 of awareness may still reduce the vaccine uptake.

References:

  • https://www.clbduoclamsang.com/wp-content/uploads/app-1.pdf
  • http://circulation.lakewaypublishers.com/ncs/publication/easttnmd/files/assets/common/downloads/MedicalDirectory.pdf
  • https://www.worldallergy.org/UserFiles/file/WhiteBook2-2013-v8.pdf
  • http://dissentfromdarwin.org/wp-content/uploads/sites/6/2019/02/Dissent-List-020419.pdf